Prophylaxis against unipolar depression.

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Bipolar and unipolar depression.

Since Kraepelin grouped affective disorders under the title of 'manic-depressive insanity', there has been controversy over whether the bipolar and unipolar entities within this are distinct affective disorders or whether they are merely two ends of an affective continuum. In order to bring some clarity and goal-posts to this argument, we define the criteria that must be fulfilled by diseases i...

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Conversion from unipolar depression to bipolar depression

BACKGROUND Clinicians, both psychiatrists and non-psychiatrists, underdiagnose bipolar disorder in a substantial proportion of depressed patients. Correct diagnosis is important since the prescription of antidepressants without mood stabilizers may precipitate a switch to mania. In patients presenting with depression, what are the odds they will turn out to really be bipolar? There are few long...

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Lithium in the episode and suicide prophylaxis and in augmenting strategies in patients with unipolar depression

BACKGROUND Depressive disorders are a leading cause of the global burden of disease and are associated with high recurrent often continuing morbidity and high excess mortality by suicide and cardiovascular disease. Whilst there are established, effective and cost-effective treatments for depression, their long-term management is often neglected: there is continuing controversy over the case of ...

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Lifestyle management of unipolar depression.

OBJECTIVE To be used in conjunction with 'Pharmacological management of unipolar depression' [Malhi et al. Acta Psychiatr Scand 2013;127(Suppl. 443):6-23] and 'Psychological management of unipolar depression' [Lampe et al. Acta Psychiatr Scand 2013;127(Suppl. 443):24-37]. To provide clinically relevant recommendations for lifestyle modifications in depression, derived from a literature review. ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1984

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.289.6444.512